7 Differences Between Sympathetic and Parasympathetic Nervous Systems

The autonomic nervous system (ANS) plays a vital role in regulating many functions that you don’t have to think about, like heart rate, digestion, and gland activity. It’s divided into two key branches: the sympathetic nervous system and the parasympathetic nervous system. While they both serve essential roles in maintaining homeostasis, their functions and effects on the body are vastly different. Here are the seven primary differences between these systems:

Differences Between Sympathetic and Parasympathetic Nervous Systems
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Primary Function

Sympathetic Nervous System

The sympathetic system is responsible for the “fight or flight” response. It activates the body to respond to stress or danger by:

  • Increasing heart rate
  • Releasing adrenaline (epinephrine) and norepinephrine
  • Redirecting blood flow from non-essential organs to muscles
  • Dilating pupils to improve vision

This system prepares the body for action and increases alertness.

Parasympathetic Nervous System

The parasympathetic system promotes a state of rest and recovery, also known as “rest and digest” or “feed and breed.” Its primary functions include:

  • Slowing down heart rate
  • Stimulating digestion
  • Supporting urination and defecation
  • Returning the body to a calm and composed state after stress

Neurotransmitters Released

Sympathetic Nervous System

This system primarily uses norepinephrine as its neurotransmitter to activate organs. Additionally, the adrenal glands release epinephrine and norepinephrine into the bloodstream, amplifying the body’s alertness and response.

Parasympathetic Nervous System

The parasympathetic neurons use acetylcholine as their main neurotransmitter. Acetylcholine helps promote relaxation and stimulates functions such as salivation, digestion, and lowering the heart rate.

Nerve Origins in the Body

Sympathetic Nervous System

Sympathetic nerves originate in the thoracic and lumbar regions of the spinal cord. The nerve fibers pass through the sympathetic ganglia, located near the spinal column, to rapidly relay signals to target organs.

Parasympathetic Nervous System

Parasympathetic nerves arise from the cranial nerves (specifically the vagus nerve) and the sacral region of the spinal cord. These nerves travel longer distances to reach their target organs.

Effects on Heart Rate and Blood Pressure

Sympathetic Nervous System

  • Increases heart rate to pump more blood to muscles
  • Raises blood pressure by constricting blood vessels

Parasympathetic Nervous System

  • Decreases heart rate to conserve energy
  • Reduces blood pressure, allowing the body to relax

Role in Digestion

Sympathetic Nervous System

The sympathetic system suppresses digestion during stressful situations by:

  • Inhibiting saliva production
  • Slowing down the movement of the digestive tract

Parasympathetic Nervous System

The parasympathetic system enhances digestion by:

  • Stimulating saliva secretion
  • Activating smooth muscles in the digestive tract to promote peristalsis

Control of Urination

Sympathetic Nervous System

This system inhibits urination by relaxing the bladder and contracting the sphincter muscles, prioritizing other bodily functions during stress.

Parasympathetic Nervous System

The parasympathetic nervous system restores bladder function by contracting the bladder and relaxing the sphincters, enabling normal urination.

State of the Body

Sympathetic Nervous System

When active, the sympathetic system puts the body’s systems on alert. It redirects resources toward survival functions, preparing the body for immediate action.

Parasympathetic Nervous System

The parasympathetic nervous system helps return the body to a state of calm and recovery, maintaining long-term health by enabling functions like digestion and immune system repair.

Summary Table: Sympathetic vs. Parasympathetic

FeatureSympathetic Nervous SystemParasympathetic Nervous System
Primary FunctionFight or flightRest and digest
NeurotransmittersNorepinephrine, epinephrineAcetylcholine
Nerve OriginThoracic and lumbar spinal cordCranial nerves, sacral spinal cord
Heart RateIncreasesDecreases
DigestionSuppressesStimulates
UrinationInhibitsPromotes
State of BodyAlert and ready for actionCalm and restorative

Importance of the Autonomic Nervous System

The autonomic nervous system is critical for survival and well-being. Damage to the nervous system may result in disorders like multiple system atrophy, impacting functions such as heart rate, digestion, and urination. By understanding the differences between the sympathetic and parasympathetic nervous system, it becomes easier to see how the body maintains balance and responds to both stress and relaxation.

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